Xarelto is taken as an oral tablet once or twice daily.It is less likely than warfarin to interact with other drugs or foods however, it does interact with some medicines.Xarelto does not need to be monitored with regular blood tests.Xarelto is the only DOAC to offer a suspension formulation. Available as oral tablets (2.5mg, 10mg, 15mg, and 20mg) and an oral suspension formulation (1mg/mL) for children and adults who cannot swallow tablets.May also be used in children from birth onwards to treat venous thromboembolism (VTE, or blood clots) or to reduce the risk of blood clots developing after at least 5 days of initial parenteral (injected or intravenous) anticoagulant treatment.Currently the only DOAC with this approval. Approved to prevent blood clots and blood clot-related events in children aged 2 years and older with congenital heart disease who have undergone the Fontan procedure.Xarelto is also approved as a preventive measure against venous thromboembolism (blood clots) in hospitalized acutely ill medical patients at risk for thromboembolic complications who are not at high risk of bleeding.Xarelto may be given to reduce the risk of major cardiovascular events (such as death, a heart attack, or a stroke) in people with long-term coronary artery disease (CAD) or peripheral arterial disease (PAD).Xarelto is also used in the treatment of DVT and pulmonary embolism (PE) (where blood clots lodge in the lungs), and to lower the risk of recurrent DVT and PE.May also be used to prevent the development of deep vein thrombosis (DVT) (blood clots in the deep veins) following hip or knee replacement surgery.Xarelto may be used to reduce the risk of stroke and blood clot formation in people with nonvalvular atrial fibrillation (AF) (a condition characterized by a specific heart rhythm disturbance).
It may also be called a direct oral anticoagulant (DOAC) (this means it stops blood from clotting). Xarelto belongs to the class of drugs known as a factor Xa inhibitor.Through its action on FXa, Xarelto makes blood less likely to clot. Xarelto (rivaroxaban) is a selective inhibitor of factor Xa (FXa), an enzyme that plays a key role in the formation of substances that cause blood clotting.Xarelto is a brand (trade) name for rivaroxaban which may be used to reduce blood clotting.Medically reviewed by Carmen Fookes, BPharm.
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